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Meridia

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Drug Information on Meridia MeridiaOrder Meridia Tablets

Brand: Meridia
Pronunciation:
mer-ID-dee-uh
Generic Name:Sibutramine hydrochloride

Common Uses of Meridia
Meridia helps the seriously overweight shed pounds and keep them off. It is especially recommended for those who in addition to being overweight have other health problems such as high blood pressure, diabetes, or high cholesterol.

It is used in conjunction with a low-calorie diet. Meridia works by boosting levels of certain chemical messengers in the nervous system, including serotonin, dopamine, and norepinephrine.

Common Uses of Meridia

Important Facts About Meridia
Make a point of keeping follow-up appointments with your doctor. Meridia can increase your blood pressure, so it's important to have your blood pressure and pulse monitored at the beginning of therapy and regularly thereafter.

Common Facts About Meridia

Directions for Using Meridia
Meridia can be taken with or without food.

-- If you miss a dose... Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.

Storage instructions:
Store Meridia at room temperature away from heat and moisture in a tight, light-resistant container.


Directions for Using Meridia

Before Using
If Meridia gives you an allergic reaction, you won't be able to use it. You should also avoid Meridia (and certainly don't need it) if you suffer from the compulsive dieting disorder known as anorexia nervosa.

Do not combine Meridia with other drugs used to suppress appetite, and do not use it within 2 weeks of taking a drug classified as an MAO inhibitor, including the antidepressant medications Marplan, Nardil, and Parnate.


Before Using

Caution
Use Meridia with caution if you have uncontrolled high blood pressure; it could make the problem worse. Avoid Meridia completely if you've had a stroke or suffer from heart disease, heart failure, or irregular heartbeat.
Also avoid it if you have severe kidney or liver problems; Meridia has not been tested under these conditions.

Seizures are a rare, but possible, side effect. If you've had seizures in the past, use Meridia with caution. If you have a seizure while taking the drug, stop using it and call your doctor immediately.

Any drug that acts on the nervous system can theoretically impair judgment, thinking, and motor skills. Meridia does not seem to have this effect, but caution is still in order until you know how the drug affects you. If you have narrow-angle glaucoma or thyroid problems, make sure the doctor knows; Meridia should be used with caution in these circumstances.

If you are prone to gallstones, be aware that weight loss can cause more of them to form. Meridia has not been tested in people under 16 years old. Meridia should be used with caution in those over 65. Although it has been classified as a controlled substance (potentially subject to abuse), the possibility of developing physical or psychological dependence is low.

Caution

Food & Drug Interaction
Remember that Meridia must never be taken within 2 weeks of using an MAO inhibitor such as Marplan, Nardil, or Parnate. The combination could lead to serious, even fatal, overstimulation.

Meridia may also interact with a wide variety of other prescription and over-the-counter drugs, especially weight-reducing agents, decongestants, antidepressants, allergy medications, and cough suppressants that contain ephedrine, phenylpropanolamine, or pseudoephedrine. Among the many drugs that pose a potential problem are the following:

Alcohol (excessive amounts) Dextromethorphan (found in many over-the-counter cough preparations)
Dihydroergotamine (D.H.E. Injection, Migranal Nasal Spray) Erythromycin (Eryc, Ery-Tab, PCE)
Fentanyl (Duragesic)
Fluoxetine (Prozac)
Fluvoxamine (Luvox)
Ketoconazole (Nizoral) Lithium (Lithobid, Lithonate)
Meperidine (Demerol) Naratriptan (Amerge)
Paroxetine (Paxil) Pentazocine (Talwin NX, Talacen)
Sertraline (Zoloft) Stimulants such as amphetamines, Dexedrine, Desoxyn, Adderall, Didrex, and Ionamin
Sumatriptan (Imitrex) Tryptophan (L-Tryptophan, Trofan)
Venlafaxine (Effexor) Zolmitriptan (Zomig)

Food & Drug Interaction

Possible Side Effects
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Meridia.

More common side effects may include: Abdominal pain, acid indigestion, anxiety, back pain, constipation, cough increase, depression, dizziness, dry mouth, flu symptoms, headache, increased appetite, insomnia, joint pain, loss of appetite, loss of strength, nasal inflammation, nausea, nervousness, painful menstruation, rash, sinus inflammation, stomachache, sore throat

Less common side effects may include: Acne, abnormal thinking, agitation, allergic reaction, arthritis, bronchitis, changes in taste, chest pain, dental problems, diarrhea, difficulty breathing, drowsiness, ear pain, ear problems, emotional changes, fever,gas, heavy uterine bleeding, herpes simplex virus, increased heart rate, increased blood pressure, itching, laryngitis, leg cramps, menstrual problems, migraine headache, muscle ache, neck pain, rectal problems, reduced vision, stimulation, stomach and intestinal inflammation, sweating, swelling, thirst, throbbing heartbeat, tingling skin sensation, urinary tract infection, vaginal yeast infection, vomiting

Rare side effects may include: Bleeding problems, kidney problems, seizures

Possible Side Effects

Special Information If You are Pregnant Or Breast Feeding
The use of Meridia during pregnancy is not recommended. If you are in your childbearing years, take reliable contraceptive measures while using this drug. If you do become pregnant, or plan on becoming pregnant, tell your doctor immediately. It is not known whether Meridia appears in breast milk; its use while breast-feeding is not recommended.
Special Information If You are Pregnant Or Breast Feeding

Recommended Dosage
Adults:
The starting dose is 10 milligrams of Meridia once daily. If you have not lost at least 4 pounds after 4 weeks, the doctor may increase the dose to 15 milligrams daily. This is the maximum; if weight loss still fails to appear, Meridia will be discontinued.

For those who experience side effects at the 10-milligram level, a 5-milligram dose may prove sufficient. Use of Meridia for longer than 1 year has not been studied.
Recommended Dosage

If You Take Too Much
Although doctors have had little experience with overdoses of Meridia, increased heart rate and blood pressure are possible results. Since any medication taken in excess can have serious consequences, seek medical attention immediately if you suspect an overdose.
If You Take Too Much
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